This comes from a brazilian saying. It basically means that if you're making jokes and someone gets offended ( on a personal level ), that is no reason to stop making those jokes. This, of course, isn't an excuse to just be an asshole, and must be used with nuance. The saying could also be directly translated to
"It's better to lose a friend than to lose a joke"
Guy 1 (whose wife died to stillbirth): Wow, these celebrities are crazy Guy 2: What happened?
Guy 1: I checked the news, and it looks like the rapper DaBaby killed his wife
Guy 2: Well, "The Baby" also killed YOUR wife
Guy 1: Low blow dude
Guy 2: It's better to miss a friend than to miss a joke
Ruler of Lake Titicaca. Rumored to have a bunghole that gets very angry if it does not receive toilet paper. Cornholio the Great is often seen walking around with his shirt over his head and his hands in the air, chanting songs about his power, and his bunghole.
"I am Cornholio! You do not want to face the wrath of my bunghole, for I need TP!"
Butthead: Shut up, Beavis! (uh huh huh huh)
Beavis: Um, okay. (heh heh heh heh).