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insanitize

To essentially wipe the mind of all sane thought (and likely replacing with insane thought, though not necessarily so), presumably from an encounter with something so incredibly insane as to have the power to do so.

This process is similar to sanitizing, but instead of removing dirt and/or germs, it removes rationale; thus, insanitize is an effective portmanteau of the words insane and sanitize.
"Don't pay attention to what he says, or he'll insanitize you with his stupidity."

{origin of phrase}
"So I was having a discussion with My Mother. The rest of the details are unimportant, logic and reason are the exclusive domain of the man." "Whut, what prompted this? Did I miss some epic fucktardation or something?" "Yes, yes you did. Be glad you didn't see it originally. This mirror alone will surely insanitize you."
insanitize by Nigrescence August 7, 2008
Related Words

hand insanitizer 

The suggestion that you need to wash your hands, and wash them again, specifically with a product that no longer exists, until you become insane with anxiety.
She had scrubbed and scoured her fingers and palms until they were raw, her bottles had all been emptied, and she was on the edge of crazy, needing to find more hand insanitizer.

sans sheriff 

Lawless use of fonts or typography, with no regard to aesthetics or legibility
I'm putting this CV straight in the bin. Written totally sans sheriff.
sans sheriff by Jamarley July 3, 2019

Breadhead 

Someone who is addicted to obtaining money and building wealth. A money addict and fanatic. Breadheads often work more than one full-time job, and some even participate in illicit activities to "obtain the bread".
A breadhead is like a crackhead, but for money instead of crack.
Breadhead by 🅱️ U S 3 4 8 March 30, 2022

Stink lines

As seen in illustrations or cartoons: Wavy, vertical lines rising above a person, place or thing. Denotes a foul odor.
"You didn't put enough stink lines on your picture of the teacher."
Stink lines by Athene Airheart March 14, 2004

schmegegge 

Yiddish slang word meaning bullshit, baloney, hogwash, nonsense, crock of shit or hot air.
I don't buy the schmegegge about Morty sleeping with Moira.
His version of the story was pure schmegegge.
The whole schmegegge was made up to get Liz a little bit of attention.
schmegegge by budsbabe February 1, 2008