Acronym for "I shat my life out", which is when you shit so hard and so much, your soul leaves your body for a minute or 2.
"Hey Mimi come have lunch?"
"Nah dude ISMLO I can't get out of bed"
"U up?"
"ISMLO....."
"Ok see you at school"
"Nah dude ISMLO I can't get out of bed"
"U up?"
"ISMLO....."
"Ok see you at school"
by SeventhFloorHawk September 10, 2018
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