Four vampires from the TV series 'Buffy the Vampire Slayer', who lived and hunted together in the late 1800s. Individually, they were: Darla, Angelus, Drusilla and William (later known as 'Spike').
After Angelus was cursed with a soul, they disbanded and went their separate ways; though they all ended up in Sunnydale, CA at some point between 1997-2003.
'So Spike, Angel, Dru and Darla...are together again?'
'Looks like. Fanged Four want another go at the glory days.'
In the lingo and culture of pimping, “fagged off” means when a ho (prostitute) leaves a pimp for another pimp. Primarily used by pimps in the first person.
I put that wet dog of a bitch Annie on the blade barefoot, and the bitchdone fagged off after her first date.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.