Another, more slangy version of saying "Fuck that Shit!".
Usually only used when speaking to someone you
know, and sometimes used with "Dude" proceeding it. Almost exclusively used when honestly hating an
idea or concept, but not used in a
sexual sense at all.
Johnny: "Hey, lets go to the movies AFTER doing our homework.
Tommy: "Dude, F that Ish! I say we go to the movies first, and
F the homework!"