Imagine a scenario where someone has just said something that has left you weirded out, disgusted and speechless. In normal circumstances a simple 'okay' would suffice, however, a combination of 'ew' and 'okay' creates the perfect word to come to terms with what you just heard.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.