E Girl Syndrome 

A disease that teen males between 14 to 19 can contract by meeting a girl online. When infected the victim will have their penis chopped off by the e girl.
Immunity is League of Legends and or Runescape with cow genocide

Man his e girl syndrome got his PP cut off

E Girl Syndrome by PepsiGromp August 25, 2019

E-Girl Syndrome

Only playing Girls in online games, pretending to be a Girl everywhere (even if you are one), picking your main Characters mainly based on genders opposed to abilities etc.

"Look at this dude, he only plays Girl Characters!" - "Maybe that person is a girl?" - "Doesnt matter, if you only play females you have E-Girl Syndrome "

E-Girl Syndrome by Voltex November 17, 2018

E-girl Quackity syndrome 

Literally just a fancy name for depression except it affects gamers.

Man I should stop gaming. I'm pretty sure I'll get E-girl Quackity syndrome eventually.

E-girl Quackity syndrome by D.d.dento April 20, 2019

E-girl Quackity Syndrome 

Another word for depression.
Usually used for a loner that is also a gamer.
Symptoms:
(Insert symptoms of depression here.)

Person: Aw damn, I'm in a really dark place right now...
E-girl Quackity: O shit you're just suffering from E-girl Quackity syndrome, my dude.
Person: Oh, okay.

E-girl Quackity Syndrome by E-girl Quackity April 25, 2019

eGirl Syndrome 

A temporary cure for depression, where a male eDates a female, the relationship often lasting one or more month(s) in which the patient feels as if his depression has been cured. When the patient is relieved of his eGirl Syndrome, his depression returns, but ten times worse.

Im happy when I'm with her. Fuck, I think I've come down with eGirl Syndrome

eGirl Syndrome by OTG Lmao January 27, 2019

Egirl syndrome 

When a male falls in love with a girl online although they have never met in real life. The female version would be eboy syndrome, but this occurs rarely. The syndrome doesn’t last longer than four months usually but may reoccur.

Guy:“I met this girl on discord and she is from Poland, i’m Thinking about moving there in the future...”
Other male friend: “dude, slow down. You got egirl syndrome.”

Egirl syndrome by A complete joke January 19, 2019