Downsydorm 

Referencing Down Syndrome, it is a purposely misspelled form that references people who are not autistic but are just straight up dumb.

Idk jack shit; A downsydorm kid could teach better than me.

Downsydorm by Subject43 April 28, 2025

Downsyndromatic 

A person who is a complete reeree.

Boogaloo is hella downsyndromatic

Downsyndromatic by JooxTheGreat September 22, 2011

Downsyndromistic 

A word you use for someone who is very retarded

Tardo: yo I think this girl likes me!
Me: what are you downsyndromistic?

Downsyndromistic by Scott’s gay June 3, 2020

downsyndrome 

Genetic condition caused by a triple chromosome also known as chromosome 21. People with this condition are blessed with the gift of eternal innocence. They are usually harmless and friendly and incapable of violence. We like to think they need help but maybe it's really us who do.

"George Bush is a perfectly sain individual, no history of downsyndrom there, he can wage war all he wants"

downsyndrome by Flo January 29, 2004

Downsyndrome 

An extremely intelligent person who doesn't deserve hatred. Please keep the negative comments about Down syndrome people to yourself. Thank you

My little brother has {Downsyndrome} and is very intelligent and adorable!

Downsyndrome by alay.s May 5, 2016

Debbie Downsyndrome 

A person who is always down and it a bad mood, and puts others in bad moods as well. Usually is in a bad mood from being ugly or gettin made fun of.

person 1: "Tough fish"
person 2: "Heis, stop being Debbie Downsyndrome for 5 min"

Debbie Downsyndrome by Todd Fisher April 21, 2008

Double Downsyndrome 

When two adults with down syndrome have a kid who also has down syndrome. Jokingly the kid would have twice as many extra chromosomes.

Double DownSyndrome
Doctor: No, you two shouldn't try for kids!
Dad: Kids? Kids!!
Kid: Nnyaa!

Double Downsyndrome by 👉😉👈 This guy February 21, 2019