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Colt .45 

*A name for a type of alcoholic beverage. The '.' before '45' may actually be absent, but I wouldn't know because I don't drink off my ass and know every name for every alchy out there.
*The nickname for the Colt M1911A1, a semiauto, 7-round, .45ACP handgun.
"You gotta drink plenty of fluids like Colt .45 malt liquor y'see!!"
-Bill Cosby.....no, he didn't really say this; it's something my older brother made up, and is a rip on what Bill Cosby said to a little girl in bed with the flu

"The Colt .45 is my most favorite handgun, or one of my most faves. It's almost one hundred years old and it would be cool to own one. ^_^ other than that it's really a powerful handgun!"
-me
Colt .45 by Dave January 18, 2004

Colt .45 

nigga put down that 40 and pick up some hen!
Colt .45 by MrGrinch August 7, 2003
a malt liquor beverage; considered a cheap way to get drunk
Let's go get some Colt 45's, it's malt liquor - it will fuck you up quicker
colt 45 by PaSCaLE March 6, 2003
1. A brand of beer (or malt liquor) with an alcohol content of about 8%. Usually favoured by people with low incomes, because of the high alcohol content and cheapness.

2. A .45 single action revolver, made by Colt's Manufacturing Company.

3. An alternate name to the song "Crazy Rap" by Afroman.
No money? That's okay, we can drink Colt 45!

Remember to cock the hammer of that Colt .45

Colt 45, and two zig zags, baby that's all we need...
Colt 45 by Kieta October 14, 2007
An efficient means to getting rid of aggravtions.
Feeling kinda down? Down a Colt 45.

Cat pissing on your car tires? Draw your Colt 45.
colt 45 by Lars Sandman December 24, 2008
its kind of like a liquored up beer that sneaks up on you all of a sudden
guy on plane: can you explain these
flight attendant: well colt 45 is like a liquored up beer that sneaks up on you all of a sudden

from soul plane
colt 45 by zach s. August 11, 2005