When one tries a new weed (marijuana) batch/strain for the first few times, one is usually more inebriated than usual so you feel more wasted than usual. Folks might act more erratic or unlike themselves.
Friend 1: Hey man you b trippin everytime you come over here!
Friend 2: That's cuz I always be having new strain brain trying out some of your trees and gettin extra funkin high you observantmotherfucker!
A temporary condition usually caused by a blow to the head, or the consumption of too much Alcohol, resulting in the inability to remember a Goddamn thing.