A B52 is an injection of 3 different drugs that is usually used on psych patients, or patients that are being combative.

It is usually given IM (intramuscular)
It consists of the following 3 meds

• Benadryl 50mg
Haldol 5mg
Ativan 2mg

It has a very calming and sedative effect on patients and very often puts them to sleep.
That patient in room 8 is flipping out!
They need a B52.. Stat!

The patient in room 8 is taking a nice little B52 nap. They needed the rest and so did we!

I think you need to B52 that patient before he starts hitting people and totally flipping out.
by Night.ER.Ninja July 27, 2014
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n. Process of defecation whereby the subject will hang from the adjacent walls of a cubicle and eject faeces into the toilet.

A childish prank often performed for a mere laugh.

Named after a military aircraft named a B52 which dropped aerial bombs from up high.

Alternatives: B.52, B52
"I couldn't help but do a B52 at Walmart. I hate that place"
by Refreshment Boxx April 4, 2010
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1. Big-ass war planes that dropped big-ass bombs on Vietnam.
2. Pop band with hits like Rock Lobster and Love Shack.
1. GI Joe drop big bomb-B52...we die.

2. How did The B52s ever get a record deal?...seriously!
by thedzone October 8, 2009
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The act of hanging from the top of a stall in a comunal restroom, ass down, in order to defficate "from above".
"dude I just b52'd"
"well did you hit your mark"
"boy did I,it was like droping neghpalm duering the Vietnam war...god dam explosive diariea!"
by B52 in school May 7, 2007
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When you’re all combative in the hospital we give this drug (B52) to you to knock you the fuck out. It’s a great nap until you wake up. B52 is also the most epic drug name ever and it really gets the point across.
Patient: “yoooo guess what?”
Other patient: “what?”
Patient: “remember that one code gray at around 7pm on march 22nd in the pediatric ED in room 1?”
Other patient: “ummm what did you do?”
Patient: “beat the shit outta the doctor for being a doctor, got B52 and everything.”
Other patient: “haha dope.”
*fistbump*
by Sacredfart March 31, 2023
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With Inpatient Mental Health, this cocktail of Benadryl, Haldol 5mg, and Ativan 2mg may be ordered to be administered to a patient acting violently towards staff or other patients. The Haldol has a great effect on psych symptoms in a fast period while Ativan takes care of certain withdrawals with sedative effects, along with Benadryl causing the patient to hopefully calm down or even take a nap. Most likely the patient will be sedated with this, and may be therefore considered a chemical restraint.

Anyways, the funniest shit about this is that while it has sedative effects, it has the same name as the B-52 bomber, the airplane responsible for dropping nukes in WW2.

If you're not in the medical field, you probably won't get this sense of humor called dark humor. Get used to it because military, first responders and healthcare workers use dark humor to survive some dark shit seen during work.
:patient starts throwing random things at staff, being violent and you call security:

:u call the doctor:

"Can we get an IM B52 on this patient?"
by Postrage22 June 17, 2023
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Term giving to the sheer size of a drugs bomb, normally done with mkat (meow) in capsule form. After consuming a B52 expect to be wiped out for a few hours. Not for the faint hearted.
Man he just done a B52 Bomb, he's gunna be gurning for hours.
by B52 expert May 18, 2013
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