Abbreviated way of saying you've already seen something. Short for "2 cool", originally "too cool for you", meaning you're too cool to be shown anything new.
Jimtrod: 2c
by randybayers January 26, 2010
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Two cents.

Written at the end of an email or online comment to show someone’s opinion. Often used with humility.
You should try wearing a different colour. 2c
by Butidontmind July 25, 2020
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Aw hell no, I'm not falling for the %2C trap
by helhoot October 19, 2021
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An abbreviation of the phrase 'Second Choice' which can be used to describe a number of things, but mainly aimed an a boy/man who has been turned to after the first choice has been lost.
'Oh man look at him with that girl, he's so 2C'
by gs1994 June 17, 2009
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2C-I or 2,5-dimethoxy-4-iodophenethylamine is a psychedelic drug and phenethylamine of the 2C family. The drug is used recreationally as a stimulant, empathogen-entactogen and as an entheogen. 2C-I is taken orally. Users of 2C-I tend to report a physical stimulant effect, often quite strong and clean at small dosages (less than 12 mg).
Person A: I tried 6mg of 2C-I in orange juice and felt awake and alert for hours without being jittery or hyper. Thingy!
by HawaiianPunch1 March 4, 2011
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An incredibly powerful psychedelic/hallucinogenicPhenethylamine, first synthesized by the famous psychedelic chemist Alexander Shulgin, and described in his book, PIHKAL.

It's very closely related to 2C-B, and still related, but much less so, to DOM (aka STP), MDMA, and Mescaline.

It is an entirely synthetic chemical, often referred to as a "designer drug", and has so far never been found in nature.

Shulgin considered it one of the "magical half-dozen".

It is very long acting, on the magnitude of LSD, where trips usually last 8-12 hours.

The dosage is relatively small; powerful effects can be felt with dosages as low as 2 milligrams, although a typical dose ranges from 10-20 mgs, with safe doses peaking around 25mgs.

The drug usually takes about an hour to take effect when taken orally, and about 15 minutes when insufflated, although it is generally accepted to be supremely safer if taken orally.

As with nearly all hallucinogens, the trip is largely subjective, and varies wildly from person to person, so a single definition of one person's experience will never suffice to properly explain the drug's effects.

Before taking 2C-E, one should properly research it, and make sure that they are in an appropriate state of mind and health to be partaking in the use of psychedelic chemicals.
Having a trip sitter and making sure you are in a comfortable and safe situaiton is imperative.

Some side effects may include temporary nausea, paranoid thoughts, and permanent changes to one's personality and psyche. Users may also experience "flashbacks" (similar to Post-Traumatic Stress Disorder) or Hallucinogenic Persisting Perception Disorder (HPPD).

It should be used with extreme caution.
2C-E is an incredibly powerful chemical and should not be taken lightly. It is not a "party drug", and rarely should it be used for "recreation".

Currently, it is available from online chemical suppliers, because it has not been specifically scheduled by the DEA, although one could technically be prosecuted by means of the Federal Analogue Act (as of June, 2004, there have been no known prosecutions).
I lost myself in the mirror for hours while tripping on 2C-E.
by Logan June 25, 2004
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