25 to life Share definition Flag 25 to life is the prison sentence for murder. If you are convicted the judge has to sentence you to a minimum of 25 years. If OJ was convicted he would have gotten 25 to life. 25 to life by redrum781 April 17, 2006 0 0 Get merch Get the 25 to life mug. Buy Now — $32.95 See more merch