Duf is a ugly fat girl in your friend ship every body has one and there friend is much hotter than she is
by Duf4466 June 23, 2020

by Smoker91113 April 24, 2009

Verb (past tense) : The act of being penetrated in one's anus by sac encased male genitalia. Often leads to a tearing of the inner anus, causing the need for stitches. Causes sticky situations when the Duffer has to tell the Duffee's parents.
by NeverBeenDuffed January 26, 2009


"Hey man, did you hear the news? last night caitie got duffed!" or "Dammit, my science teacher duffed me on that lab report."
"Are you really gonna duff me like that?"
"Are you really gonna duff me like that?"
by C...punk35 May 26, 2012

by ineedabbl September 1, 2023
