The Matthew Perry combo is when you get high on both ketamine and buprenorphine at the same time. (His previous heart/artery issues combined with this combination is what caused his death, not the combo itself). You will indeed get zooted off your ass if you take this combo, and is a phenomenal concoction of scientific wonders that will take you from the 3rd dimension to the 3.5th dimension.
Dude, my friends and I took the Matthew Perry combo last night and got fucking blasted. Those buprenorphine strips are weak as fuck though, so we had to double down. Weak ass fucking government opioids, next time we'll have to try the lil peep combo.
by Dfenley December 8, 2024
Get the Matthew Perry Combomug. by Lilandy May 27, 2023
Get the Perry madrinmug. Like a bread bowl. Perry Bowles is the act of eating a hearty soup. (Typically a mixture of beef stew and rice). After ingesting the mixture, you lick the females anus and upon inserting your tongue. Barfing in between in cheeks (which is the potato bread) into the butthole. Thus filling the asshole with a hot soupy mixture.
by Turk92 December 15, 2019
Get the Perry Bowledmug. The man over there is a perry.
by drftr November 20, 2023
Get the perrymug. 
A literary dumbass that thinks he can beat anyone with small muscles on both arms. Does math really well and also doing well in school, probably does wrestling but never had a serious game before. He probably wears glasses and sit on his ass all day playing children games ironically.
by Avonnned November 10, 2022
Get the casey perrymug. The slightly chubby sassy queen of the grade, she is a huge theater dork but also a complete savage and the best in bed.
by Ethansarmpitmustard October 27, 2018
Get the Perrymug.