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Up with Hope, Down with Dope

a slogan (using rhymns) that's been used in the past by the Rev. Jesse Jackson.
Up with Hope, Down with Dope sounds like a positive notion, but when the children grow up and have to face the problems and stresses of life where dumbasses are in unearned positions of power and they try to influence every aspect of our lives then some may lose hope. Then how do they try to cope and meet demands? You guessed it - DOPE!
by I Saw U2 Live Twice January 14, 2009
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Dope As Fuck

This phrase is similar to others such as
totally cool
totally sweet
insanely awesome
insanely bitch'n

It is most commonly used to refer to the band Funeral Moon and other asscore bands
some Guy: dude, funeral moon is dope as fuck
Some other guy: yeah they ripped ass at the show last night
by Jonas Hill November 26, 2007
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Related Words

i'm broke as a joke, 24-7 on dope

broke. what you and all your friends most likely are, espec. if you do have a lil ice-cream habit.
"so u wanna go to the movies?" "i can't babe, i'm broke as a joke, 24-7 on dope"
by lauren September 1, 2003
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dial-a-dope

Drug-dealing operation where drug dealer(s) are contacted by phone and/or text messaging to distribute drugs.

(Hey drug dealers, if my definition is inaccurate .. please submit your own definition)
Police believe the "dial-a-dope" dealers were receiving hundreds of telephone orders each week.
by too-many-grouchy-people January 16, 2007
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dichloro-diphenyl-trichlorothane

Most commonly known as DDT, this is a chemical that was widely used as a pesticide (particularly for mosquito control) in the 1990's before being banned across the board by all states.
If I were to kill a midget, perhaps the best methos would be to lace his drink with a little dichloro-diphenyl-trichlorothane.
by C. Dub November 7, 2006
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Most Dope

Originated From Mac Miller a rapper from Pittsburgh, Pennsylvania as a life style similar to the "Taylor Gang" by Wiz Kalifa about smokin weed, stayin fresh, and gettin bitches. It also refers to Mac Miller's groupe of homies.
yo Best Day Ever is Most Dope!
by Macmillersdope April 4, 2011
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diphenhydramine

Diphenhydramine is most known for its active properties in over-the-counter antihistamine benadryl. Very good for taking care of allergies, but drowsiness is a significant concern. For this reason, it's often used as a sleep aid.

Also used frequently for a cheap, fast high. Causes visual and auditory hallucinations, dizziness, confusion, delirium, and finally sedation. Makes music, breathing, and movement pleasing. Negative side effects from overdose include cottonmouth, irregular urination, amnesia, and erectile dysfunction.
I took 600 mg of diphenhydramine last night and could have sworn my house was on fire and the teapots were singing to me...
by LaDiablo May 15, 2006
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