When someone is piss pilled, it means that they are generally an angry person who is always pissed off, and will likely be miserable their whole lives
due to their constant irritability. Dubbed piss pill because of the whole red pill/blue pill whatever pill concept of the matrix, but unlike the other
pills, the piss pill makes it's users live a live of "pissful ignorance," or live a
life where everything sucks and they'
re always pissed off.