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melting the mouse 

When you turn on your air conditioner but it burns up because a mouse crawled inside. Also a term for male masturbation.
"Hey, can we get some air in here? I'm sweating balls from all this melting the mouse."
"Nah, man, I hit the thermostat earlier but I think I melted the mouse."
"RIP soulja boy"

chi-city mouse 

A person from Chicago and Chicagoland suburbs who is delicate, refined, and nimble
chi-city mouse by Chittyfidy May 20, 2017

Southern Brunswick Mouse Maneuver 

The act of inserting a colleagues' pc mouse into the own vagina in order to show dominance over that bitch.
Colleague A: "E. is being a real snitch again!"
Colleague B: "Guess it's time for another Southern Brunswick Mouse Maneuver."

Texas Road Mouse 

Common to urban areas of Texas, it is defined as a young, shy prostitute.
1: Did you see that Texas Road Mouse?
2: Yeah, tried to hire her once, but she was so shy I had to ask for a refund

one eyed mouse wearing a turtle neck 

Wow!!! His one eyed mouse wearing a turtle neck is weird...

Click on the mouse 

Have sex
Yo are you going to click on the mouse