Sis 

girl mentally ill who doesn't know what's going on

falls in love at people who are terrible don't respect her and hate her
everyone who was friends with her hates her and wishes her death
she loves herself

loves to talk about her feelings
her astro birth chart say she is awful person

Sis you can't fall in love with him, he's an imitation of a man, he's not even a half man

Sis by Borntodiesis July 8, 2021

Sis 

A lil thang a 42

Girl, he tried kicking down my door.
Nah bitch you needa get you a lil sis.

Sis by Kay12345555 September 28, 2021

Sis 

Sis is the noun for describing a queen who is in shock.

Ciara: Omg i met Sammy last night

Ben: OMG sis

Sis by Ciaranadben October 14, 2021

Sis 

A word used to replace argh when seeing or hearing something disgusting. It can also be used when someone is acting like a bitch or a slut.

Person A: Cow manure is edible and nutritious in India.
Person B: Sis, that's disgusting.

Person A: I had sex with 5 dudes today.
Person B: Sis!

Sis by Thedarklol October 15, 2021

Sis 

Sis means slaves in suffering

Look at my good sis.

Sis by Black J December 19, 2021

sis 

sis meaning slave in suffering

your a sis aren’t you

sis by dwntwrry December 20, 2021

Sis 

South African slang meaning, gross or disgusting or shameful.

Ag no SIS , that guy is picking his nose!!

Sis by kz22x February 4, 2022