Commonly used in Internet memes and real life.
It is an insult to say to someone if you are losing an argument or just to ruin someone's life. It is also just to say for comedic effect in a conversation or out of the blue.
The gastrointestinal phenomenonexperienced by many people after they eat Popeye's Chicken including, but not limited to, explosive and watery diarrhea, uncontrollable flatulence, and upset stomach. Normally lasts until the next ferocious bowel movement.
We had Popeye's for lunch and now Amanda has a terrible case of Popass. It's EyE-ASS-Poppin' bad.