Uno 

The name of the hardest, most intense game in the whole world. Any skilled Uno master deserves respect.

person: I wish I was an Uno Master!

Uno by iEatSpam June 27, 2018

Uno 

The Game That Ruins Friendships

what happens after playing Uno:

"You were supposed to use a reverse, not a wild card, Carl!"

"I hate you, Jack!"

"Well, those two have ended their friendship."

Uno by Your Local Weirdo March 24, 2020

uno 

short/txt language for "you know"

dudess: im a dragon uno , a fire dragon2!!
dude: no shit ino, ur born in 76
dudess: wtf howd uno dat?

uno by lozory May 19, 2008

Uno 

The magical word required to say before you die or you live for 2 more years

"DAD!... NO!"
"uno..."
"oh it's fine now"

Uno by ItsJayJack July 25, 2018

uno 

uno means one in Spanish

Jose - lets count in Spanish
Ben - I dont know how to Jose
Jose - just start off by saying uno

uno by Dat_Fr3$h_Gurl December 22, 2005

Uno 

-An old card game
-The beginning of a song like 1,2,3...

I was playing Uno with some friends while one of the began a song by saying Uno, dos, tres...

Uno by for you to decide July 6, 2003

Uno 

A man born with one nut

Tc McNeill from salem high school in rockdale county Georgia

Uno by Anonymous February 27, 2003