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Used with a hashtag (#) on Twitter to tag Twitter threesomes. Tweesome is a group of three Tweeple, F/M/F, sharing cyber sexual public Tweets i.e., engaging in group cyber sex via Twitter. Tweesome posts are properly tagged #tweesome. Often associated with #swingers.

If the number of people engaged in Twex is four or more, it is properly tagged #Tworgy. If the number of Tweeple is three and they are M/F/M, it is tagged #twangbang. If the number of people engaged is just two, it is simply Twex.
As used in a Tweet:

I'm totally up for a #tweesome! Who's naked? See my free videos at link!
Tweesome by twittertwat June 17, 2009
Related Words

Treesome 

When two people have sex up a tree. Yes, the tree is like and extra person there alot you and do with it ... use your imagination!
Derek: Let's have sex
Ronnie: Ok
Derek: Just you, me and the tree
Ronnie: Ohhhh, a treesome you thoughtful bastard
Treebranch: Ohhhhh baby ...
Treesome by PrezMeister January 1, 2008

Treesome 

A threesome with one girl and two guys.
"Yo, what's a treesome?"
"It's just like a threesome, but with more wood"
Treesome by JGreenFruit September 1, 2013

Treesome 

A threesome or threeway where two (or all three) of the members are in the same family tree.
Becky is such a slut, she had a treesome with the Dailey cousins.
Treesome by Alek K. October 17, 2008

Treesome 

A threesome or threeway where two (or all three) members of the orgy are related (part of the same family tree).
Becca had a treesome with the Bailey cousins.
Treesome by Nutwrap October 20, 2008

Thweesome 

A threesome with an Asian.
Hey baby, how about we spice things up with a thweesome?
Thweesome by El SpiCock October 10, 2011
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