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A very uncomfortable vagina wedgie (formally known as a twat wedgie, hence "twedgie") when a woman's underwear rides up the lips of her vagina and creates a vivid display for all the public to see and laugh at. Men with vaginas can get them too.
dayum! that vagina has one mean twedgie!!
Twedgie by Jaegermeister69 March 7, 2009
Related Words
It is a wedgie in the front.
That girl know her pants are too tight, look she got a twedgie.
Twedgie by realb337 September 25, 2011
-A twat wedgie.

-When your underwear gets in the creveses of your vagina, causing discomfort.
Carol: What are you doing?

Katy: I'm picking my twedgie.
Twedgie by Twatolina October 1, 2011
A taint wedgie

When your boxers/boxer briefs ride up into the area between your asshole and nutsack causing discomfort
I leaned forward while sitting down and got a killer twedgie.
twedgie by SinfulHoliday December 28, 2009
It’s like a wedgie, but in your twat.
:Man, I have a horrible twedgie right now.
:Pick that shit!
Twedgie by Welp_im_Fuked October 17, 2018

thwedgie 

Where, when a girl is wearing a thong, the thong gets pulled up so it is wedged in between her butt cheeks. This is also known as a wedgie. It can be very painful.
I was wearing a thong, and jack came up and gave me a killer thwedgie!
thwedgie by ~Claire~ November 7, 2005