tmdwu

That’s most definitely what’s up. Used by Wyomingites who are goth sexy bad boys to express strong agreement.
Ozzy Osbourne doing heroin. TMDWU!
by Nick1288 April 19, 2024
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TMDWU

Stands for That’s Most Definitely What’s Up.

Variation of TWU- That’s What’s Up.

Common utterance of the lolcow species known as King Cobra JFS; an emphatic variation of That’s What’s Up, when something is *especially* bitchin’.
Cobes: This jalapeño, bacon and Hi-C Ecto Cooler mead that I made hardly has any botulism in it, TMDWU!
by Trash K April 10, 2024
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tmdwu

That’s most definitely what’s up or that is most definitely what is up. Popularized by the fan/trolls of YouTube icon, King Cobra JFS.
by Hybridjap April 29, 2024
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tmdwu

Acronym associated with KingCobraJFS in a YT music video titled as above. Means "That's Most Definitely What's Up."
by saltifry August 21, 2024
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