The Shnits 

This refers to the condition of having the shits or diarrhea. Part of the Matt-E-Okee lingo created while staying at the Boca House. Alternatively, the word shnit can be used in place of theshit.

Jesus Christ! You wouldn't believe it. I've got the shnits again!

The Shnits by Matt-E-Okee July 22, 2010

aint with the shits

basically means you aren't down with something

bruh try this lean!
nah man i aint with the shits

aint with the shits by dustybelle January 21, 2017

have the shits 

To have diarrhea. To go to the bathroom and evacuate your bowels in liquid form.

It can also be used if you have a lot of belly pain and have to go constantly to the bathroom for number two.

Poor Mary, she has the shits.
My cat had the shits last night.
I think I have the shits.

have the shits by NAjA November 26, 2013

So With The Shits 

So with the shits means when you’re vibing.

*dude dancing to a song*
spectator- “Why’s he so with the shits?”

So With The Shits by .Lazarus January 2, 2020

With the shits 

Chicago term. It means the opposite of lacking. To be "with the shits" means to be in direct possession of enough of physical protection for the amount of illegal merchandise (work) you are currently attempting to move. On the South Side of Chicago, holding any amount of work requires at least a sidearm; larger amounts of work call for additional crew members and more guns. If another crew is able to take your merchandise by force then you are lacking and are not at all with the shits. Popularized by many Chicago rappers, perhaps most notably by Fredo Santana on his track "My Lil Niggaz".

Outside of Chicago, the term has loosely come to mean simply a willingness to engage the types of illegal activities commonly discussed in popular hip hop music. If you're actually in Chicago, however, it's important that the original definition be observed at all times. You absolutely do not want to get caught lacking in the field.

Real Chicago Hood Nigga #1: Say bruh, ain't you afraid of getting run up on by the opps?
Real Chicago Hood Nigga #2: Who, me? Hell nah, fuck them pussy ass niggas, my lil niggas with the shits bruh. Shit... I wish they would try to run up, fuck around and get they whole crew taken out, homie we don't play.

With the shits by robo042 September 13, 2016

Off the shits

Short term is OTS, This means a person is either high drunk or rolling. Rolling is the slang term for high on a pill. Originated in Chicago but now known wide because of a rap group known as GBE.

Just smoked a thoint i'm off the shits

This flat got me off the shits

Sippin on this hen i'm off the shits

Off the shits by ChicagoNative February 11, 2013

The shits of it

The state of being totally over something.

I totally need to move out of this backward town...I have the shits of it!

The shits of it by timmy leary September 25, 2010