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spleesh! 

Exclamation often used by Amy on Futurama to express disgust, frustration etc. Synonymous with "duh!" after somebody says something stupid.
Amy: "Fry, alcohol kills brain cells."

Fry: "No I'm doesn't!"

Amy: "Spleesh!"
spleesh! by overflow parking August 3, 2010
Related Words

Spleesha 

The act of inhaling a sheesha and a spliff at the same time.

Spleeshing is commonly performed when stoned

Side affects include - partial blindness
Salutations companion, fancy trying a spleesha?

Hey man, want to go spleesh?

OMG he's spleeshing his fucking balls off.

Dude i was totally spleeshless last night

Fuck man, dan's having a spleeshure!
To shoot the slide piece out of a bong due to a coughing or laughing fit while taking a hit
Jimmy spleshed his bong the otherday and put a hole in the wall
splesh by Kevlarmunkey112 August 2, 2007
A term that can be used to reference having sex. This term can also be used to describe a hot women.
I mo spleesh dees hoes.

I almost spleeshed this girl last night but some retard walked in the room.

Damn son look at those fine ass spleeshies over there.
Spleesh by Ruuuus_bucket August 11, 2010
1. Needing to go to the toilet.

2. The sound your piss makes when it's aimed into the toilet perfectly; also like a Swish in basketball.
"I need to spleesh"

"BRB I just need to spleesh"
Spleesh by Jack Patros October 7, 2008
To sleep or sleeping, tired and ready for bed
Mom, I spleashing by Dan's tonight ok?
Spleash by DBird September 6, 2007