spikinosis 

When you fart and it feels like you’re being stabbed in the asshole by a spike.

Gee Ricky, when I farted last night I had spikinosis.

spikinosis by ColumbusCupKid March 2, 2023

spicanosis 

An increasingly popular, and more geographically correct, reference to the H1N1 influenza virus (swine flu). This terminology incorporates the locality of the cesspool of origin of the virus.

Yo, Marco won't be hittin' ya back this week cuz he down with da spicanosis shit.

spicanosis by Heinrich Jablome May 5, 2009

Skinosis 

A rare and often fatal disease of the skin, usually localized in the large extremities of the body. Skinosis is characterized by a rapid and prolonged deterioration of skin cells; a common skinosis patient will have several black or brown patches of decayed (or decaying) skin distributed sporadically around the area of infection.

Although not contagious, studies have shown that skinosis has a fatal tendency to spread throughout the patient's body in a remarkably short period of time; often resulting in a complete loss of skin, and, ultimately leading to grotesque, saucy-red zombie-like patients; very close in appearance to some more severe burn victims.

To this date there is no known cure for skinosis. Doctors and scientists around the world are currently working round the clock for a remedy, but thus far have made little progress. If you do happen to contract skinosis, consult a physician immediately. Depending on the severity of the case you may have to have a body part amputated to cut off the infection at the source.

Doctor: "Mr. Jones, your test results came in; they don't look good. I'm afraid you have skinosis... of the skin."

Patient: "Skinosis of the skin?! That's the worst kind!"

Skinosis by Chrishack September 1, 2005