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sissypoo 

a bitter, hateful, mean-spirited cruel ass bitch (that may or may not have had a sex change operation) that you are related to and HAVE to see on holidays and other family events. Can be used in the place of BITCH if bitch has been trivialized by over used at family events.
Is fucking sissypoo going to ruin Christmas again this year for the whole family. Who is the asshole that invited sissypoo to the family reunion. Did you see how rude sissypoo was to the waiter, I bet he spit on the bitches food when she sent it back. I got sissypoo'd when that bitch showed up for Thanksgiving.
sissypoo by unfortunate sis February 15, 2010
Words you can keep
Sissypops is the meaning of telling someone to man up or grow a pair
Person 1: dude did you hear Kevin backed out of the fight

Person 2: yeah it made him out to be a real sissypops

Person 1: I totally agree Kevin is the biggest sissypops ever
Sissypops by C.scall August 3, 2019
Another term for sister. Usually used in a cute way.
A term of endearment.
I love her, you know? She's my little sissy-poo!

He is really mad at me because I dated his sissy-poo.

(singing) Happy birthday to you, my sweet sissy-poo!

Jenny can't come to the movies, she has to babysit her sissy-poo. (giggling)
sissy-poo by Juergen February 6, 2007

sissyboo 

Like Your Sister, Shes Been There For You Since Diaper Days & Still Is.
(Kelly sees Mari stand up for May in front of a bully)

Kelly: Talk About Braveness? haha. What was that for?
Mari: Shes my sissyboo, no one messes with her. Bl
sissyboo by _Polynesianbabe_ July 17, 2013

sissybooin 

when i mans cryin bout a girl
that bitch was sissybooin bout his ex
sissybooin by kayplay trevino March 6, 2008
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