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When your mate/family member has seriously injured themselves or is in a lot of pain and is obviously not ok, but you ask anyway wasting precious time that could save a life. Well done.
'Jeffery Falls off Cliff'
Tim "Jeffery R U OK?
".........." said Jeffery

Jeffery died 2 seconds after.
R U OK? by Millao August 14, 2021

Annie R U OK? 

A line that Michael Jackson keeps repeating in his song "Smooth Criminal" for no apparent reason.
MJ: Annie r u ok?

Q W E R T Y U I O P A S D F G H J K L Z X C V B N M M N B V C X Z L K J H G F D S A P O I U Y T R E W Q Q A Z W S X E D C R F V T G B Y H N U J M I K O L P P L O K I M J U N H Y B G T V F R C D E X S W Z A Q 

THIS IS THE FINAL STAGE OF BOREDOM!!!! ONCE YOU HAVE TYPED THE QWERTY KEYBOARD ACROSS AND BACKWARDS AS WELL AS DO THAT SIDEWAYS AND SIDEWAYS BACKWARDS, BUT THAT'S NOT ALL YOU STILL HAVE TO ADD THE SPACES IN BETWEEN EACH LETTER. THEN ONCE YOU DO ALL THAT YOU HAVE ACHIEVED GOD LEVEL!!!!!!
Person#1:Do you know that girl that typed Q W E R T Y U I O P A S D F G H J K L Z X C V B N M M N B V C X Z L K J H G F D S A P O I U Y T R E W Q Q A Z W S X E D C R F V T G B Y H N U J M I K O L P P L O K I M J U N H Y B G T V F R C D E X S W Z A Q into the urban dictonary?

Me:*SCREAMS AND FLASHBACKS TO EXACTLY WHEN I TYPED Q W E R T Y U I O P A S D F G H J K L Z X C V B N M M N B V C X Z L K J H G F D S A P O I U Y T R E W Q Q A Z W S X E D C R F V T G B Y H N U J M I K O L P P L O K I M J U N H Y B G T V F R C D E X S W Z A Q INTO THE URBAN DICTIONARY*

Person#1:*confused*
ruok; pronounced (Are You OK) is the short form for finding out how someone is doing. The usual reponse to this is imok.
How's it going Imek? Ruok?
Response: Imok. Thanks.
ruok by Imek Rohew March 11, 2008
Someone who definitely eats pizza rolls. A god of some sort. Some may call him a GOAT but he likes to referred to by Sir Ruok.
What a RUOK
Ruok by Cdogg2018 August 8, 2018

BTW RUOK 

If your friend is sick you will say "by the way are you ok"
BTW RUOK by Katherine November 23, 2003