When a guy is on the verge of going out with a a girl, but he has one or several other girls he plans to hook up with first and doesn't want tp ruin his chances by making one girl his girlfriend.
A: "Man Kelly's really pushing me to ask her out, but I want to hook up with Heather and Ashley first"

B: Sounds like you got a bad case of the players syndrome.
by C_Dizzle October 19, 2006
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When a person gets minorly injured or insulted and acts like you broke their legs or just called him a slur that insults him and everything he stands for. Generally seen in Twitter users and stans
Normal Person: Stop acting like I killed your entire family. I made a silly joke about Dream.

Soccer Player Syndrome victim: Shut up you Dreamophobic pig!
by Haywired4 May 9, 2021
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When online game players (and generally unskilled ones) think that the game revolves around them. This is most likely due to them playing solo games... Or being an only child.
A: Man, what is up with this Ashe. She keeps getting caught and is blaming support and jungle.

B: Yep, she must have first player syndrome.
by Do you voodoo magic June 4, 2017
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One person habitually dominating another, much like Player 1 in a multiplayer game. Usually stems from too much time in a socially-stressful environment.

Can only be treated by a punch in the face from a close friend.
Guy: *grabs the remote* we're watching this now!

Girl: ugh your Player 1-syndrome is resurfacing again!
by BadWolfFile July 28, 2010
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the inability to effectively play a multi-player video game in a position other than player one; the result of frequently playing a game yourself.
I'm not going to be able to beat him if I start every round from this position. I've been playing this game so long by myself that I'm now suffering from player one syndrome.
by eddie arias July 7, 2006
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The feeling you get when you can no longer distinguish a tangible understanding of reality, you feel that you are at the centre and nothing else is real, like you are player 1 in life and that everything else only exists when you are there and that other people are only NPC's (Non-Player Characters).
I think I'm suffering from Player One Syndrome I cant tell what is real, like I'm Player 1 in my own video game.
by Keneth Palin July 9, 2014
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When playing a split screen game and you end up looking at the winners play area where you start to believe it's your screen. You eventually believe it's you who is winning or doing great and start to feel amazed with how good the game is going. At the end of the round or near it, you are flooded with embarrassment as you realize you have been staring at the wrong play area for an unknown amount of time thinking you were playing it where in reality your player has failed to advance. Could also happen in real life.
I thought I was finally getting the hang of things until the Player 2 Syndrome set in.
by thedjwcc February 12, 2022
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