Top definition
When a guy is on the verge of going out with a a girl, but he has one or several other girls he plans to hook up with first and doesn't want tp ruin his chances by making one girl his girlfriend.
A: "Man Kelly's really pushing me to ask her out, but I want to hook up with Heather and Ashley first"

B: Sounds like you got a bad case of the players syndrome.
by C_Dizzle October 18, 2006
Get the mug
Get a players syndrome mug for your girlfriend Beatrix.