the inability to effectively play a multi-player video game in a position other than player one; the result of frequently playing a game yourself.
I'm not going to be able to beat him if I start every round from this position. I've been playing this game so long by myself that I'm now suffering from player one syndrome.
by eddie arias July 7, 2006
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The feeling you get when you can no longer distinguish a tangible understanding of reality, you feel that you are at the centre and nothing else is real, like you are player 1 in life and that everything else only exists when you are there and that other people are only NPC's (Non-Player Characters).
I think I'm suffering from Player One Syndrome I cant tell what is real, like I'm Player 1 in my own video game.
by Keneth Palin July 9, 2014
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The urge to be first, the center of attention, or the front runner in any aspect of day-to-day life, the term deriving from the multiplayer video game position of "player one".
Fred has player one syndrome: he always has to have the first controller, otherwise he gets upset and doesn't play.

Marge has been really controlling lately. Maybe she has player one syndrome?

Why does Layla think she can get whatever she wants if she throws a tantrum? She's such a player one.
by kemist97 October 31, 2022
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