piss-off Share definition Flag It's like saying 'get out of my face' with one notch of higher verbal aggression. what is your problem , get away from me .Why don't you just beat it, pal , get away from my face, piss-off ! piss-off by coolmind January 29, 2006 0 0 Get merch Get the piss-off mug. Buy Now — $32.95 See more merch