permatweaker

people who have been tweaked so long that they are now permanently tweaked out. aka life long crack head.

tommy has been a crack head for so long he has now gained the title of permatweaker.

by bevis85 May 28, 2009

Permatweeked

Former dope heads that still show signs of previous drug abuse by twitching, talking out the side of their face, may appear to be trying to bite their own ear...

Girl 1: "Damn, what the hell is wrong with that twitchy bitch?"
Girl #2: "Oh, don't pay her no mind, that bitch just permatweeked!"
Girl #1: "Whoa, I am not ever doing meth!!!"
Girl #2: "I know that's right..."

by heatedpoet July 9, 2016

permatweaked

Permanently brain damaged from methamphetamine used. Also known as fried.

Fucker is permatweaked, jackjawing, looking out of the corner of his eyes, quick screwed up thinking, and not able to reason.

by gayburns7 March 8, 2015