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migraine farmer 

A really tough course or other brain-torturing exercise, eg programming, advanced calculus or effective ventriloquism. Symptoms include poverty due to the rising cost of Advil and long hours crying and asking "Why the hell did I enroll in this?" to random strangers on the street.
Example 1

Tom: There goes Luke again. Ever since he went into advanced computer programming, he's been literally insane.

Jerry: Yeah, that course is a migraine farmer all right.

Example 2

Man, ever since I started trying to imitate Jeff Dunham, I've realized how much of a migraine farmer ventriloquism is! How does he do it?
migraine farmer by ABeefyRhino November 16, 2009

Migraine 

Let it be said what the headache represents
It's me defending in suspense
It's me suspended in a defenseless test
Being tested by a ruthless examiner
That's represented best by my depressing thoughts
Clique member: "I-I-I-I've got a migraine, and my pain will range from up down and sideways."
Normal person: "Oh yeah dude migraines suck."
Clique member: "No you don't understand."
Migraine by Ayeeeeeeeboss September 4, 2016

megraine 

A common complaint of celebrities and wannabes, a megraine is a severe headache caused by incessantly talking about oneself and focusing on one's problems without ever stopping to consider how fortunate one is and how other people have genuine problems.

Though not a serious medical issue, a megraine can cause sufferers to be incapable of functioning normally or permorming routine tasks for themselves - like wiping their own arse.
"bla bla bla bla bla bla me bla me bla bla bla bla bla bla bla bla bla ble me bla my life is so hard bla bla bla bla..."

"Sounds tough... er...Ms Hilton do you think you can go out now and show your face at the party we've paid you hundreds of thousands of dollars to host for charity.."

interrupting: "bla bla bla me bla bla bla what do they want from me bla bla bla bla so hard bla bla bla bla bla I HAVE A MEGRAINE bla bla bla"

Migraine 

/'mî,grän/
(Noun)

It's you defending in suspense,
you suspended in a defenseless test
Being tested by a ruthless examinant
That's represented best by your depressing thoughts.
TØP Fan: "I've got a migraine..."
Normal Person: Aw, dude I'm sorry.
TØP Fan: No, I'm just singing tf?
Migraine by MarshTheTransBoy December 17, 2017

Migrainsterbation

Masturbating while having a migraine
Migrainsterbation causes too much pain to be worth the effort.
Migrainsterbation by Bunneh45 October 14, 2009

masgraine 

A masgraine is a strong thumping headache you get occasionally while masturbating,this can get very painful when you orgasm and slowly pass after ejaculation.
i had a killer masgraine earlier dude
yeah what were you jerking to?
i was watching fisting on the net for four hours ,when i shot my muck.it felt like my head was going to explode!