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One of the nicknames for the late, great Luther Vandross.
Lutha.
originated from malnurished pot-bellied ethopian kids in latter part of the 20th century.

1. meaning to have a rank taint.
2. a reference towards sexual inuendo.
3. lack of erections among the asian male population.
1. Damn dude, did you wash that rank ass lutha?
2. Sup hoe, how bout i put some of this lutha on that ass?
3. I would but Chang Chin is still battling a severe case of the lutha.
lutha by bob sinclair January 31, 2004
It mean it's OVER. It is a reference to the late Luther Vandross...

It means it is dead and gone.. it's time has passed... it is over, period.

Often times used when the speaker is really over the subject and wants to rub in the fact that it is so over and done that it will never be again.
It's lutha!
Meaning: "It's over." "It's dead." "It is no more."
Lutha by WeedQueenoftheSouth November 6, 2020
LUTHA

" Leave Us The Hell Alone!! ".
LUTHA by Debil999 October 23, 2022

Chat Lethal 

When finishing an opponent in Hearthstone, assume that every card costs 0 mana, opponent has no taunts or secrets, all spells and abilities can hit face, all minions have charge and immune to silence/freeze, and that arithmetically 2+2=9.
Retard #1: "OMFG KRIPP SO BAD MISSED LETHAL"
Retard #2: "wtf why hit senjin and not wrath+starfall face?"
Retard #3: "WOW LETHAL MISSED"
Guy #1: "he only had 3 mana... chat lethal"
Retard #4: "have you noticed children's pee smells like turnips?"
Chat Lethal by Ryaii March 7, 2014

Lethal Interjection Crew 

The crew which Thugnificent, Macktastic, Flonomial and Leonard are part of. This crew is in the Adult Swim show The Boondocks.
You hear the song Stomp 'Em in the Nuts by the Lethal Interjection Crew?? Yeah I love that song.
Lethal Interjection Crew by Perli February 17, 2012