Something that is mandatory to say when you do something that is usually hard and now you must do it again because of unknown circumstances. Frequently said when encountering Sans in a dark alleyway and accidentally playing 'Hey Ya' by Outkast a second time. Originally from GTA: San Andreas.
That thing you say when you have to do another annoying thing again like work, school, taking care of your fucking kids dad why don’t you come back please Ryan
Meaning. The “Ah Shit, Here We Go Again” meme is used to express deep-seated distress. When conflicts are never-ending, or you can't seem to catch a break, the ah shit, here we go again one-liner adequately represents upset. Clever individuals have used the scene to describe a Buddhist who's died and been rebirthed.