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Fed the fuck up. When you're half way through getting done with exams and can't take it anymore. It can also refer to being extremely bored or even just annoyed at work. People may also use FTFU in reference to someone being annoying or when you can't be bothered doing more chores.
'There's so much to learn. I'm so FTFU!'

"Work is slow today. Im FTFU and just want to go home"
FTFU by nikster January 19, 2014
Related Words
Ftfu FTFUW
Fucked the fuck up.
In reference to extreme levels of inebriation from alcohol, weed, or other drugs. Usually posted as a facebook status, sent as a text message, or exclaimed as 'FUCKED THE FUCK UP'

The origin of the term seems to be as a variation of the popular STFU.
FB: Nat G is FTFUUU

Text: im soo ftfu sadf

Exclaimed: THIS SHOTS FOR YOU! I'M FUCKED THE FUCK UP!
FTFU by 508WeekendWarrior May 1, 2010
Short for freeze the fuck up. You say this when you're pissed off that something you put in the freezer isn't freezing fast enough.
Joe: I really wish this beer would hurry and ftfu..
Ftfu by Bringin88 August 26, 2009
When you wanna give strength for the word "FTW" and "FTUW" (FTW = For the win, FTUW = For the ultimate win"), so you're saying:
For The Fucking Ultimate Win
Dude, did you see the second season of 30ROCK?
Yes ofcourse! 30ROCK FTFUW
FTFUW by cjori October 27, 2008
For The Fucked Up Win.
Dude...The South Park 'Goobacks' episode FTFUW
FTFUW by Nick_08 August 30, 2007