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extra chromosome 

What makes a Down's Syndrome person how they are.
Timmy has an extra chromosome, that's why he goes to special school.

Extra chromosome weed

weed so strong that once inhaled you feel the retarded effect that an extra chromosome has on the brain. In many cases this cannabis can and will make you shit your pants without any warnings. Dumbed down this weed is described as the bees knees if the bees knees were 10 piece mcnuggets straight from God's lotion sack.
Woah bro (random grunt noise) this Extra chromosome weed got me absolutely zoinked.

mr extra chromosome

person one: have you heard of mr extra chromosome?
person two: velvet? yeah.
person three: hey!! dont be transphobic!!!!!!!!!! its a she

Yo chromosomes got extra homes 

The most devastating of any yo or ur insults, possibly deadly
Tommy: hey Leo, Yo mum gay
Leo:Yo chromosomes got extra homes
Tommy:*ceases to exist*

Stink lines

As seen in illustrations or cartoons: Wavy, vertical lines rising above a person, place or thing. Denotes a foul odor.
"You didn't put enough stink lines on your picture of the teacher."
Stink lines by Athene Airheart March 14, 2004

schmegegge 

Yiddish slang word meaning bullshit, baloney, hogwash, nonsense, crock of shit or hot air.
I don't buy the schmegegge about Morty sleeping with Moira.
His version of the story was pure schmegegge.
The whole schmegegge was made up to get Liz a little bit of attention.
schmegegge by budsbabe February 1, 2008