To use the SPT Labtech chameleon instrument for automated cryogenic electron microscopy (CryoEM) sample optimization, to ameliorate sample behavior that limits specimen quality and information available in reconstructed molecular maps. CryoEM is the go-to method for biologists to determine the structure of cellular and molecular targets involved in important functional pathways to cure disease.

I will send out some samples to the New York Structural Biology Center to chameleorate and they will send back for imaging.

chameleorate by 140pointsix May 5, 2022

Related Words

chameliorate • chameleorate

murderhobo

In a tabletop game, a murderhobo is a player who murders NPCs indiscriminately. This is normally derogatory, referring to a player who totally ignores quests, dialog, backstory, trade, world building etc.

The term is most common with Dungeons and Dragons, but it can be applied to most RPGs where the player is allowed to kill most quest-giving NPCs and NPC traders. E.g. Elder Scrolls, Fallout, Divinity original sin.

DM: The sad little orphan girl tugs at Steve's trenchcoat to get his attention, and ask for help saving her pet dog from...
Steve: I'd like to roll a strength check against strangling the orphan.
Dave: I call dibs on the dog.
DM: You murderhobos disgust me.

murderhobo by Loup&S September 9, 2021

Word of the Day on September 22, 2026

Whale

In sales terms, a whale is a prospect that is significantly larger than an organization’s average customer.

Whales are large and extremely difficult to close. Due to their immense size, they are highly sought-after.

A whale is typically identified at first by a whale hunter on the sales team, but often requires cross-discipline participation in order to close; this includes assistance from operations, engineering, creative, client success, and business development teams.

"Shit...the sales director chewed me out on the sales call this morning. He's totally pissed that I have nothing in my pipeline. I've been focused on this one whale for so long that I haven't had time to prospect for normal-sized deals."

Whale by FQ_GFY February 3, 2020

Word of the Day on September 21, 2026

Concrete cowboy

A guy who thinks he's a country kinda guy, but in reality lives a comfortable city / suburban life.

Eugene: Look at that dude in the cowboy hat!
Todd: He's just a concrete cowboy.

Concrete cowboy by EugeneJohnson42000 March 16, 2024

Word of the Day on September 20, 2026

hobo loko

any hard liquor that is cheap & potent.. eg. relska, popov, potters, evan williams, kamchatka, fireball, rumpleminze, southern comfort, everclear

hey let's get a drink of that?

go ahead
*takes drink* ugh wtf is that?

everclear & bepsi
fucking hobo loko eeessshh

hobo loko by d i z k o 2 0 8 September 14, 2026

Word of the Day on September 19, 2026

God Shot

A chance happening with profound meaning, an unexpected blessing, a "sign".

Dr. Drew on Celebrity Rehab said "All of a sudden what had been just another Hollywood proposal became for him an unexpected blessing, an opportunity for growth. In drug recovery language, that's called a "God shot."

God Shot by Imogen1564 February 25, 2011

Word of the Day on September 18, 2026

city chicken

A food native to Pittsburgh/Western Pennsylvania in which cubes of pork and/or veal are put on a short, wooden skewer, breaded, then baked and/or fried.

I've heard that city chicken originated during the Great Depression, when folks didn't have enough money to buy full cuts of meat, so they assembled meat scraps on a wooden skewer, creating a make-shift drumstick. Hence the name.

Are yinz havin' city chicken for dinner?

city chicken by TRF August 31, 2006

Word of the Day on September 17, 2026