annoyitate Share definition Flag verb, uh-noi-i-teyt an intentional act in which the victim will experience a combination of extreme annoyance and maximum irritation. "Mom, my brother's annoyitating me again!" Mimicking your brother can really annoyitate him. annoyitate by u can 2 August 27, 2012 0 0 Get merch Get the annoyitate mug. Buy Now — $32.95 See more merch