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Whaddupdoe? 

Whaddupdoe- interj. v. (whad-up-dough) is a colloquial greeting for "what's up though?", "hello", "what's up?" "Peace!", "hey!".

Through relaxed speech methods, this terminology originated in the streets of Detroit circa late 70's, early 80's.

Whaddupdoe can also be used in both exclamatory and interrogative forms.

Let's create a scenario...
Person A- Whaddupdoe Cuzzo?!? (another formal Detroit greeting).

Person B and replies back by saying "Whaddupdoe?"
Related Words

whatupskee 

Created by rapper JJ Demon. It's the crunk way to say what up bitches? Or how's it going. It is slang too. Or sup? Anything that is asking some one whats going on. Whatupskee?
Yiz-zoh! Whatupskee bizznitchez? Whats crackin hoes?
whatupskee by LaceSixxTheDemon June 27, 2011

wutupdoe 

"What's up brother?" in terms used in the movie 8 Mile
*at seeing your close homie at any location*
-Wutupdoe
-Nutin' chillin, nigga
wutupdoe by T. Herm October 24, 2007

Whaddupdoe 

Whaddupdoe- (what-up-doe) is a colloquial greeting for "what's up though?", "hello", "what's up?" "Peace", "hey".

Some examples of informal colloquialisms can include words (such as "y'all" or "gonna" or "wanna").
Through relaxed speech methods, this terminology originated in the streets of Detroit circa late 70's, early 80's.

Whaddupdoe can also be used in both exclamatory and interrogative forms.

Let's create a scenario...
Let's create a scenario...

Person A just pulled up on the block and greets Person B by saying "what up cuz?"(another formal Detroit greeting).
Person B and replies back by saying "whaddupdoe!"

whudupdoe 

It virtually means: what's going on, how are you doing, what's happening, etc...it is a saying that is Born, Bred and Said by most Detroit Natives.(may also be spelled, "What Up Doe")
The man walked into the store and as he passed a young man that was leaving out and he said to him, Whudupdoe? The young man said the same in return. A simple greeting of affection and acknowledgment of people you pass, meet or greet!