wutupdoe Share definition Flag "What's up brother?" in terms used in the movie 8 Mile *at seeing your close homie at any location* -Wutupdoe -Nutin' chillin, nigga wutupdoe by T. Herm October 24, 2007 0 0 Get merch Get the wutupdoe mug. Buy Now — $32.95 See more merch