it is the same as whats up
what up dude
by tommy November 25, 2002
What Up is a phrase commonly used by Barney Stinson, usually heard at the end of a comically appropriate sexual comment, often accompanied by a high five. Its style varies from time to time as do most of Barney's catchphrases, being either high-pitched or low-pitched, oddly pronounced or even not verbally said.
Barney: Open bar for the guys, open casket for the ladies, what up!
by hakunama tata July 21, 2019
Whats up with me and you. When are you gonna let me get some.
Boy: Ayo, Whats up with the whats up?
Girl: Fuck outta here, I got a man. No Single Ladies shit.
Boy: ....Fraud.
by Ctfu February 10, 2010
A phrase used to ask about something odd, or what the point of something is. The word "that" can also be replaced with whatever noun the person is asking about. It is also common to inerject the word "fuck" into the phrase to express shock or discust.
What's up with the smirk?
Look at all those bags on the road. What's up with that?

Person1: What the fuck's up with your hand!?
Person2: Ahh! Why are you just standing there?! Take me to the fucking hospital!
by Cinymin86 November 16, 2009
Meaning that you fully understand and/or agree and find yourself excited about the idea or suggestion proposed.
Friend 1: "Yeah so I'm thinking we chill before, and then hit the club by 9. Got mad beer at the crib anyway"
Friend 2: "That's what's up"
by KelsBels April 6, 2008
What is happening wiht you, How are you, whats going on?
Something that LouAnn doesnt understand.

Usual response: Nothin Much
**Do not reply 'HI' or with another 'Whats Up'**

A common phrase that most people understand & use each day.
Carl: Hey Dude
Mark: Hey Whats up?
Carl: nothin much
Mark: Cool
by Ednabrowneye13 January 18, 2009