when the lips of the female genitalia are so large from getting banged and abused, that she can twist them into a knot. Seen it. It can be done.
The striper at Mel's bachelor party, tied her Twat in a knot!
by GoNe1 May 17, 2007
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It's like the expression, "don't get your panties in a bunch." Literal meaning is to not get worked up.
Just because I slept with your sister, don't get your twat in a knot.
by JStine May 20, 2012
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A Man bun (hair cinched up on top of the head, rolled into a very small ball).
The barrista hipster young dude at Starbuck$$ had a twat knot on his head.
by SweetPete SweetPete September 16, 2017
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Another slang term for the man bun
Girl: You see that man bun on that guy?

Girl #2: Yeah, total twat knot
by Dickhead92 September 11, 2017
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When a girls pussy lips are so loose they get knoted together with the thong
When i was walking in school i felt an extreme amount of pain in my twat and i looked and i had a huge twat knot
by Fin Germatwat October 31, 2010
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A person that does not return your calls, text messages etc. in a timely manner.

Q. Did she call you back?
A. No, she is such a Twat knot!
by Squish79 July 28, 2008
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