Tight Booty Syndrome (TBS) Share definition Flag to be nervous, to choke. LeBron got Tight Booty Syndrome (TBS) when the game was on the line, Very Funny! Tight Booty Syndrome (TBS) by Ecnerwal23 July 25, 2009 0 0 Get merch Get the Tight Booty Syndrome (TBS) mug. Buy Now — $32.95 See more merch