Thothead Share definition Flag a cross between thot and pothead. it is to be used when there’s a thot that is always stoned. person 1: i heard she is a hoe person 2: she’s always smoking weed tooperson 1: sounds like a thothead Thothead by 2140127 April 23, 2020 0 0 Get merch Get the Thothead mug. Buy Now — $32.95 See more merch