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The Seth Rogen

1) When you're pretty high and you can't keep your gut in

2) feeling bloated after eating a dope ass snack
1) Dude I'm so high, im doin The Seth Rogen
2) I feel like Seth Rogen bro
by Smalltownassbutt May 4, 2019
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The Seth Rogen Gene

A gene that when injected into your bloodstream gives you the appearance of being funny even though you've said nothing funny
You: So what's this one?
Doctor: The Seth Rogen gene, it gives you the appearance of being funny even though you've said nothing funny.
You: Oh... Hey doc are we done here? I gotta grab some beers with the fellas.
Doctor: HAHAHA! THAT IS HILARIOUS!
by BigJ91 September 29, 2011
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The seth Rogan effect

The effect when a actor play's the same person in every movie.
The Seth Rogan effect means he play's basically the person in every movie he has appeared in.
by Joe_mama_666999 April 19, 2022
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What I call homo-sapien who are addicted to perianal abscesses.
Person 1: Are you addicted to perianal abscesses?
Person 2: Yes.
Person 1: Joseph James Rogan & Seth Aaron Rogan: The First Juvenile Release.
by LeSouffleDeVersailles February 8, 2025
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