When you've held in a shit so long that you have to run to the bathroom and barely make it on the toilet.
May or may not involve bad cases of diarrhea.
"OMGG!! Get out da way!! I'M SHIT RUNIN'!!!!"

"Dude, my mom got mad at me when I shit ran to the bathroom while we were having 'serious discussion'."

"Oh damn, I think I'm gonna have to shit run soon!"
by -lexiie December 3, 2009
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ringing somebodys doorbell, taking a ginormous dump on the step and running for your life whilst doing evil laughs ...
Bobby: What do you want to do tonight?
Jimmy: lets shit & run at marias house
Bobby: lets do it

later maria opens her door

Maria: ahhhh what the fuck is this thing ahhhhhh ... mmm tastes good...
by Abi and Katie July 4, 2008
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When you can't hold your shit in and you have to stop at a random building just to use the bathroom.
Guy #1: Dude, what took you so long?

Guy #2: Sorry I had to do a shit & run.
by Applesowce8572 December 23, 2016
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When someone walks their dog, but does not bring a bag with which to clean up the poop, and has to flee the scene.

Having no intention of cleaning up after your dog.
Friend: "Man, that dude's dog just shit in my yard and he didn't clean it up!"

Me: "Oh! It was a shit and run!"
by The 1st Lady February 25, 2018
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When someone takes a shit and clugs the toilet without telling the owner of the bathroom!
by zacherzach November 6, 2016
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Like a hit and run but involving taking a shit. It's any shit that is performed in under two minutes, thus leaving no time to wipe, wash your hands, or flush. So you drop trow, shit, pull up, and go. The next person into the stall knows they've been the victim of the shit and run.
Shit Sergeant: "Alright maggots we're doing the two minute drill, the shit and run on my whistle!!"
by bangbangletchyanutshang April 16, 2005
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Taking a massive, hellacious dump in someone else's bathroom (especially a stranger/acquaintance), then leaving swiftly and pretending that nothing happened.
Person 1: Hey man, why are you in such a hurry? We just got here ten minutes ago?

Person 2: Get your coat. I just took a massive shit in this dude's bathroom, and I want to get the hell out of here before he finds out it was me.

Person 1: So...shit-and-run?

Person 2: Exactly.
by Clockwork Lime October 21, 2009
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