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RG-syndrome 

It stands for Ruru-Genshin syndrome. Someone's computer/laptop/mobile is said to have RG-syndrome when their device lags/crashes excessively due to low RAM/ crappy graphic card/ shitty wifi- usually happens while playing Genshin Impact but might occur during other times too.
Person 1: Man, my laptop's been laggin like shit. Ion know what's happening.
Person 2: LMFAOO L bozo. You've got RG-syndrome duh.
RG-syndrome by Eleanor8014 November 25, 2023
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RG Syndrome 

to have RG Syndrome you must be unable to receive an erection. One who suffers from erectile dysfunction.
teen 1: I heard Tom Cruise has RG Syndrome. Do you know of any truth is this?

teen 2: I don't know, you'd have to ask his wife.
RG Syndrome by MAK+NPH=LIFE February 16, 2009